Cissus quadrangularis is a succulent climber with green stems and branches. The stems are quadrangular in shape, buff coloured with greenish tinge, dichotomously branched, sub-angular, glabrous, fibrous and smooth, often leafless. They are winged but the wings are never corky. The tendrils are opposite the leaves.

Cissus quadrangularis might have antioxidant, pain-relieving, and anti-inflammatory effects. It might also help stimulate bone growth. People use Cissus quadrangularis for obesity, fractures, joint pain, low bone mass, and many other conditions, but there is no good scientific evidence to support most of these uses.